FOXBOROUGH, Mass. — Quarterback Tom Brady, playing on the 14th anniversary of his first NFL snap, handled the top ranked defense in the NFL and led the New England Patriots to their seventh straight win, a 34-9 rout of the Detroit Lions on Sunday.

Brady, who relieved Drew Bledsoe at the end of the Detroit rout on Thanksgiving Day almost a decade-and-a-half ago, threw for 349 yards and two first-half touchdowns to tight end Tim Wright. It was the 63rd 300-yard game of Brady’s career, tying him with Dan Marino for third place on the NFL’s all-time list.

Running back LeGarrette Blount, re-signed by the Patriots on Tuesday after his release by the Pittsburgh Steelers, also scored two touchdowns, both on short runs and the first on his first carry. He added a 23-yard run in the third quarter and a 33-yarder in the fourth and finished with 78 yards on 12 carries.

The win was the Patriots’ 15th straight at home, six of the wins this season, and was also New England’s 14th straight over the AFC North, the longest current streak by any team against any division. It also ensured the Patriots (9-2) of their 14th straight winning season, third-most ever by an NFL team.

The Lions, who came in No. 1 in the league in scoring and rush defense, failed to score a touchdown for the second straight week and fell to 7-4 with their second straight loss.

Brady, who finished 38 of 53, was picked off at the Detroit goal line by safety James Ihedigbo in the third quarter — only the third red zone interception of Brady’s career to go with 140 red zone touchdown passes.

He has 20 touchdown passes and two interceptions during the winning streak — and Sunday became the sixth quarterback in NFL history with 7,000 pass attempts.

Wide receivers Julian Edelman and Brandon LaFell caught 11 and nine passes, respectively, while running back Shane Vereen had eight catches, as the Patriots rolled up 439 yards of offense.

Detroit quarterback Drew Stafford was 18 of 46 for 264 yards and an interception — to go with a 49.5 passer rating.

Matt Prater was three of four on field goals for the Detroit scoring, while Stephen Gostkowski kicked two field goals for New England.

Danny Amendola had an 81-yard kickoff return to set up New England’s second touchdown.

NOTES: Rookie RB Jonas Gray, who ran for 201 yards and a club-record four touchdowns last Sunday night at Indianapolis before being sent home from practice Friday, reportedly for being late, was in uniform but did not play. … Since 2010, the Patriots are 22-3 in the second half of seasons. … RB Reggie Bush was inactive for Detroit because of an ankle injury and the Lions lost LB Ashlee Palmer to a head injury in the first half. … The 14 straight winning seasons by the Patriots trail only the 16 recorded by the San Francisco 49ers (1983-98) and Dallas Cowboys (1970-85). … The Lions host the Bears on Thanksgiving Day, while the Patriots have a big game at Green Bay next Sunday. … Patriots RB LeGarrette Blount worked out a deal with S Don Jones for his No. 29, Blount’s number before he left — and Jones wore No. 31.