ORCHARD PARK, N.Y. — A dominant defense made life difficult on Green Bay Packers quarterback Aaron Rodgers, as the Buffalo Bills forced three turnovers, kicked four field goals and added a punt return touchdown to stay alive in the AFC wild-card race with a 21-13 win on Sunday.

The Bills (8-6) held Rodgers to a career-worst 34.4 passer rating and snapped the Packers (10-4) five-game winning streak. Rodgers completed 17 of 42 passes for 185 yards, threw two interceptions and failed to throw a touchdown pass for the first time all season.

Buffalo sealed the game with a late safety after Green Bay took over at its own 10-yard-line with 1:58 remaining and no timeouts. Defensive end Mario Williams stripped Rodgers at the goal line, and running back Eddie Lacy recovered in the end zone.

Mason Crosby kicked a 34-yard field goal to cut Buffalo’s lead to 19-13 with 4:53 remaining.

Bills safety Bacarri Rambo made his second interception of the game — and second of his career — after the Packers had driven from their own 2-yard-line to the Buffalo 34. Rambo’s 28-yard return gave the Bills a drive start near midfield and Dan Carpenter converted a 43-yard field goal to put the Bills in front 19-10 with 9:23 left in the fourth quarter.

Rodgers was intercepted for the first time in six games when Rambo made his first pick late in the third quarter. It was also the Packers’ first turnover in five games.

Patriots 41, Dolphins 13

FOXBOROUGH, Mass. — New England took care of the formality of clinching its sixth straight AFC East title with a rout of Miami.

Cornerback Kyle Arrington romped 62 yards and somersaulted into the end zone after a blocked field-goal attempt early and the Patriots broke open a close game in the third quarter to wrap up their 11th division crown in the last 12 years.

New England (11-3) has nine wins in its last 10 games and can ensure home-field advantage throughout the AFC playoffs with wins in its final two games.

The win kept the Dolphins (7-7) from becoming the first division opponent to sweep a season series from the Patriots since 2000 while also moving New England to 24-1 at home in December since 2003. The Patriots are 7-0 at home this season.

Colts 17, Texans 10

INDIANAPOLIS — Andrew Luck threw two touchdown passes and Indianapolis beat Houston to win its second straight AFC South title.

The Colts (10-4) have a three-game lead on Houston (7-7) with two regular-season games remaining. Luck finished 18 of 34 for 187 yards and two touchdown passes.

Any hope of victory for Houston was essentially wiped out with 13:17 remaining in the second quarter when quarterback Ryan Fitzpatrick suffered what was reported to be a fractured left leg while attempting to scramble for a first down. Fitzpatrick was transported from the field to the locker room on a cart.

Bengals 30, Browns 0

CLEVELAND — Cincinnati spoiled the debut of Cleveland rookie quarterback Johnny Manziel with a smothering defense and a strong running game to cruise over its Ohio rival.

Cincinnati piled up 244 rushing yards and three touchdowns. Bengals rookie Jeremy Hill scored two rushing touchdowns in the first half and Rex Burkhead scored on a 10-yard run with 23 seconds to play.

The Bengals (9-4-1) remain in front of the Baltimore Ravens and Pittsburgh Steelers in the AFC North. The Browns (7-7) have lost three straight and four of their last five games to fall off the pace in the conference playoff race.

While the Browns managed 107 total yards, the Bengals played like a first-place team from start to finish. Manziel had a 27.3 passer rating, completing 10 of 18 passes for 80 yards. Manziel was picked off twice in the first half.

Ravens 20, Jaguars 12

BALTIMORE — Jacksonville quarterback Blake Bortles was sacked eight times and Baltimore overcame a lackluster performance by the offense and sloppy penalties to escape with a victory.

The win keeps Baltimore (9-5) in the hunt for one of the AFC’s six playoff spots. Jacksonville (2-12) has lost six of its past seven games.

The Ravens’ leading rusher, Justin Forsett, limped to the sideline after taking a hard hit in the second quarter and was limited to 48 yards on 16 carries.

Ravens quarterback Joe Flacco responded with an 82-yard drive that ended with a 3-yard touchdown pass to tight end Owen Daniels that gave the Ravens a 17-12 lead with 8:34 left in the third quarter. Flacco completed 20 of 30 passes for 221 yards.

Steelers 27, Falcons 20

ATLANTA — Running back Le’Veon Bell scored two touchdowns and quarterback Ben Roethlisberger and receiver Antonio Brown set franchise records to help Pittsburgh keep control of its playoff destiny with a win over Atlanta.

The Steelers (9-5) remained a half-game behind Cincinnati in the AFC North with their second straight win. The Falcons (5-9) dropped out of first place in the NFC South.

Roethlisberger didn’t throw a touchdown pass, but finished with 360 passing yards to set a Pittsburgh single-season passing-yards mark, topping the record of 4,328 yards he set in 2009. Roethlisberger now has 4,415 passing yards this season.

Brown caught 10 passes for 123 yards and broke Hines Ward’s franchise record for receptions in a season. Brown has 115 catches this season, two more than Ward had 12 years ago.

Panthers 19, Buccaneers 17

CHARLOTTE, N.C. — Derek Anderson threw for 277 yards and a touchdown as Carolina defeated Tampa Bay to remain alive in the NFC South playoff race.

Graham Gano kicked four field goals, including one from 45 yards out with 8:31 remaining for a 19-10 lead, and the Panthers needed to go only 4 yards for their lone touchdown.

Anderson, filling in because Cam Newton was injured in an automobile wreck five days earlier, completed 25 of 40 passes.

The Panthers (5-8-1) won for the second week in a row and they will be in first place in the NFC South if the New Orleans Saints lose Monday night at Chicago. The Bucs are 2-12.

Chiefs 31, Raiders 13

KANSAS CITY, Mo. — A close game at halftime disintegrated into a Kansas City rout of Oakland.

The Chiefs (8-6) held a 10-6 lead early in the third quarter, but then scored three touchdowns with quarterback Alex Smith throwing a pair, including a 70-yarder to running back Knile Davis. Meanwhile, the Chiefs’ defense stepped up, keeping the Raiders bottled up in their own end of the field for most of the game. Smith threw for 297 yards, completing passes to 10 different receivers.

The victory ended Kansas City’s three-game losing streak and kept alive its hopes of making the field for the AFC playoffs. The Raiders (2-12) are in contention for the first selection in the 2015 draft.

Giants 24, Redskins 13

EAST RUTHERFORD, N.J. — Eli Manning threw three touchdown passes to rookie Odell Beckham Jr. and the New York Giants rallied to beat Washington.

Beckham did not enter the lineup until Week 5 because of a hamstring injury, but the Giants’ first-round pick has the look of a superstar. He finished the game with 12 receptions for 143 yards, his NFL-record seventh straight game with at least 90 receiving yards. The Giants (5-9) won their second straight after seven straight losses.

The Redskins (3-11) had a golden opportunity on the final play of the first half to take control of the game. Quarterback Robert Griffin III, in when starter Colt McCoy left the game after the first series with a neck injury, took off for the end zone and initially appeared to have crossed the goal line for the touchdown. Replays showed that Griffin didn’t have control of the ball. Officials ruled the play was a 7-yard gain and a fumble out of the back of the end zone for a touchback.