Philadelphia Eagles (5-1) at Arizona Cardinals (5-1)

Sunday, 4:05 p.m. ET, at University of Phoenix Stadium, Glendale, Ariz. – TV: FOX

*TV announcers: Chris Myers, Ronde Barber, Jennifer Hale

*Keys to the game: The Cardinals are third in the NFL with a plus-seven turnover ratio, which keeps them in every game and pinches opponents who are loose with the ball. The Eagles (minus-1) spread the ball around but their pace-based offense thrives on the running game. It finally got what was expected of LeSean McCoy, who averaged 95.3 yards from scrimmage in three career games against the Cardinals, before the bye week.

The Eagles are known for their shotgun offense, but QB Nick Foles was under center for 22 of 71 offensive plays in Week 6. Thirteen of those plays were McCoy runs, providing him more time to read the defense and for coach Chip Kelly to implement more cut-back runs to keep the defense honest.

Cardinals QB Carson Palmer is 10-2 in his past 12 starts and while he’s not running the level of flammable offense Foles does for the Eagles, Palmer has settled in as a perfect extension of coach Bruce Arians. While veering away from LB Connor Barwin (six sacks in his last three games), Palmer should have time to look for his diverse collection of pass catchers. Jitterbug rookie WR John Brown is elusive after the catch but the Eagles will try to stick him off the snap to disrupt Palmer’s timing. The Eagles expect to be in plenty of nickel and dime packages with Arizona’s ability to go to four- and five-receiver sets.

*Matchup to watch – Cardinals RB Andre Ellington vs. Eagles LB Mychal Kendricks: Philadelphia’s top defensive player could return just in time for a grueling workout, shadowing three-down back Ellington and emerging backup Stepfan Taylor, the focal points of the Arizona offense who are more dangerous as receivers than runners. *Player spotlight – Eagles TE Zach Ertz: So committed to the running game are the Eagles that they’ve moved away from Ertz in base packages, leaving him to play just over half of the offensive snaps because he is a liability as a blocker. But he’s also a knockout in the red zone and caught two touchdowns last season in a win over Arizona.

*Fast facts: Of the teams to start 6-1 since the 1970 merger, 89 made the playoffs, only 17 did not. … The Eagles have converted just 40 percent of their red-zone opportunities into touchdowns. In the past 10 years, only one team has reached the postseason with a red-zone touchdown rate lower than 40 percent.

WHO WILL WIN AND WHY

Arizona’s underrated home-field edge could come into play but only if the steady Cardinals keep the game close into the fourth quarter. A back-and-forth game would eventually see the Cardinals tap out.

*Our pick: Cardinals 27-23