Oakland Raiders (0-6) at Cleveland Browns (3-3)

Sunday, 4:25 p.m. ET, at FirstEnergy Stadium, Cleveland – TV: CBS

*TV announcers: Spero Dedes, Solomon Wilcots

*Keys to the game: Injuries at the heart of the offensive and defensive lines caused a major letdown at Jacksonville last week and the Browns are still making adjustments. The massive defensive line combo of Phil Taylor and Ahtyba Rubin is unlikely to be back, which suits the Raiders just fine. Interim head coach Tony Sparano wants to be physical and establish the run, and Cleveland was flattened by a weakling running game of the Jaguars a week ago. A steady diet of Darren McFadden will be thrown at the Browns’ 32nd-ranked run defense (155.2 yards per game), until they establish they can stop Oakland’s downhill attack.

Raiders rookie QB Derek Carr is becoming a strong leader with poise and presence despite a lackluster supporting cast. The Browns are solid in the secondary but with a makeshift front seven, Carr could have more time to pick his spots.

The Browns have a no-nonsense rushing attack ranked sixth in the NFL at 133.5 yards per game and use their backs to finish drives with a league-best eight touchdowns. Jacksonville thwarted the inside running game with speed, and took away the anticipated counter-punch of play-action passes from Brian Hoyer. Hoyer is just 24 for 58 in the past two games, and an early bout of inaccuracy could bring Johnny Manziel into the equation. Watch for TE Jordan Cameron, who has just 10 catches all season, to be heavily targeted in the first half.

*Matchup to watch – Browns FS Tashaun Gipson vs. Carr: Carr is careful with the ball. The rookie second-round pick has thrown eight touchdowns compared to five interceptions in six games. Gipson preys on mistakes and forced throws with four interceptions already in 2014 – three a direct byproduct of QB pressures – and seven picks in his past nine games.

*Player spotlight – Raiders DE Benson Mayowa: With LaMarr Woodley (biceps) out the Raiders will turn back to Mayowa, a noted athlete with pass-rushing skills who was strong against the run last week when Woodley went down. He spent last season with the Seattle Seahawks and made the Raiders primarily because of his athleticism. “You have to do it all,” Mayowa said. “You can’t be a one-trick horse these days. To stay around, it’s play all three downs.”

*Fast facts: The Browns have won five of the past seven meetings. … Raiders PK Sebastian Janikowski has 46 career field goals of 50-plus yards, six shy of Jason Hanson’s NFL record.

WHO WILL WIN AND WHY

Cleveland gets back to the winning ground game to move over .500 with another one-win team (Tampa Bay) visiting next week.

*Our pick: Browns 27-20